Selon un rapport de la société pharmaceutique Frontier Biotech, des médicaments anti-VIH dénommés inhibiteurs de fusion, l’albuvirtide est le premier médicament chinois associé de l’anti-retroviral Kaletra, a donné de bon résultat.
Selon l’étude réalisée sur ce régime unique fusionnant deux médicaments dont le premier essai date de 2013, après quatre semaines d’utilisation, le virus est indétectable sur 41% des patients recrutés pour les essais, alors que 85% ont eu un traitement efficace.
Ce nouveau médicament cliniquement sûr représente une grande avancée dans la lutte contre le VIH, puisque d’après les constats de la Commission nationale de la santé, en 2020, environ 1,25 million de patients vivaient avec le VIH en Chine, un pays où environ 80 000 personnes contractent le virus chaque année.
Ce premier médicament développé en Chine pour le traitement du VIH, dont le nom génétique est l’albuvirtide, appartient à un groupe de médicaments anti-VIH appelés inhibiteurs de fusion, qui bloquent l’entrée du virus à certaines cellules du système immunitaire.
En effet, les résultats de l’essai clinique de phase III, qui a duré 48 semaines, ont été publiés dans le Journal of Infection et ont montré que l’association de l’ABT avec l’anti-rétroviral Kaletra présentait un bon profil de sécurité.
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